EARLY TAVR
EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
AI Description
This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with clinical surveillance (CS) in asymptomatic patients with severe, calcific aortic stenosis.
- Who can join
- older adult
- Participants
- 901
- Expected completion
- 2032-03
- Funded by
- industry
Conditions studied
Aortic Stenosis, Severe, Heart Diseases
What is being tested
- DEVICE: Edwards SAPIEN 3 / SAPIEN 3 Ultra THV
What it measures
- All-cause death, all stroke, and unplanned cardiovascular hospitalization, The number of patients that have any of these conditions, When all patients have reached 2-year follow-up
Centers Participating
These centers are participating in this study. Reach out to them directly to learn more.
Abbott Northwestern Hospital
Minneapolis, MN
Albany Medical Center
Albany, NY
Allegheny General Hospital
Pittsburgh, PA
Atrium Health Carolinas Medical Center
Charlotte, NC
Banner – University Medical Center Phoenix
Phoenix, AZ
Baylor Scott & White The Heart Hospital – Plano
Plano, TX
Brigham and Women's Hospital
Boston, MA
Cape Cod Hospital
Hyannis, MA
Carilion Roanoke Memorial Hospital
Roanoke, VA
Cedars-Sinai Medical Center
Los Angeles, CA
CentraCare – St. Cloud Hospital
Saint Cloud, MN
Charleston Area Medical Center
Charleston, WV
Cleveland Clinic
Cleveland, OH
Dartmouth Hitchcock Medical Center (Lebanon)
Lebanon, NH
Emory University Hospital
Atlanta, GA
Endeavor Health Evanston Hospital
Evanston, IL
Froedtert Hospital
Milwaukee, WI
HCA Florida North Florida Hospital
Gainesville, FL
Henry Ford Health (Detroit)
Detroit, MI
Hoag Hospital (Newport Beach)
Newport Beach, CA
HSHS St. John's Hospital
Springfield, IL
Huntington Hospital
Pasadena, CA
Inova Fairfax Medical Campus
Falls Church, VA
Intermountain Medical Center
Murray, UT
Kaiser Permanente San Francisco Medical Center
San Francisco, CA
Kaleida Health
Buffalo, NY
Lankenau Medical Center
Wynnewood, PA
M Health Fairview University of Minnesota Medical Center (East Bank)
Minneapolis, MN
MaineHealth Maine Medical Center (Portland)
Portland, ME
Mayo Clinic (Rochester, Minnesota)
Rochester, MN
MedStar Washington Hospital Center
Washington, DC
Memorial Hermann-Texas Medical Center
Houston, TX
Mills-Peninsula Medical Center
Burlingame, CA
Montefiore Einstein Hospital (Moses Campus)
Bronx, NY
Morristown Medical Center
Morristown, NJ
Mount Carmel East
Columbus, OH
Newark Beth Israel Medical Center
Newark, NJ
NewYork-Presbyterian Hospital
New York, NY
Northwestern Memorial Hospital
Chicago, IL
Ochsner Medical Center – New Orleans
New Orleans, LA
OhioHealth Riverside Methodist Hospital
Columbus, OH
Piedmont Atlanta Hospital
Atlanta, GA
Providence Regional Medical Center Everett
Everett, WA
Providence Sacred Heart Medical Center & Children's Hospital
Spokane, WA
Providence St. Patrick Hospital
Missoula, MT
Rochester General Hospital
Rochester, NY
Rush University Medical Center
Chicago, IL
Saint Luke’s Hospital of Kansas City
Kansas City, MO
Sentara Norfolk General Hospital
Norfolk, VA
Stanford Health Care
Stanford, CA
Stony Brook University Hospital
Stony Brook, NY
Swedish Cherry Hill Campus
Seattle, WA
Texas Health Dallas
Dallas, TX
The Christ Hospital
Cincinnati, OH
UC Davis Medical Center
Sacramento, CA
UCHealth Medical Center of the Rockies
Loveland, CO
UF Health Shands Hospital
Gainesville, FL
UNC Health Rex (Raleigh)
Raleigh, NC
University Medical Center
Charlottesville, VA
University of Iowa Health Care
Iowa City, IA
University of Maryland Medical Center
Baltimore, MD
University of Washington Medical Center
Seattle, WA
UPMC Harrisburg
Harrisburg, PA
Vanderbilt University Medical Center
Nashville, TN
WellSpan York Hospital
York, PA
Yale New Haven Hospital
New Haven, CT
Registry entry updated 2024-05-13
Deciding whether to join a study is your choice, and you can ask a study team questions before you decide anything.
If you would rather we did it with you, call us on (656) 206-4686.