APOLLO
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
AI Description
Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.
- Who can join
- adult, older adult
- Participants
- 1056
- Expected completion
- 2036-07-07
- Funded by
- industry
Conditions studied
Mitral Valve Regurgitation
What is being tested
- DEVICE: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
What it measures
- MAC Cohort, All-cause mortality, 1 year
- Primary Cohort, Composite of all-cause mortality or heart failure hospitalization, 1 year
Centers Participating
These centers are participating in this study. Reach out to them directly to learn more.
Tampa General Hospital
Tampa, FL
Abbott Northwestern Hospital
Minneapolis, MN
Aurora St. Luke's Medical Center
Milwaukee, WI
Baptist Medical Center Jacksonville
Jacksonville, FL
Barnes-Jewish Hospital
Saint Louis, MO
Baylor Scott & White The Heart Hospital – Dallas
Dallas, TX
Baylor Scott & White The Heart Hospital – Plano
Plano, TX
Baylor St. Luke's Medical Center
Houston, TX
Beth Israel Deaconess Medical Center
Boston, MA
Bon Secours St. Mary's Hospital
Richmond, VA
Brigham and Women's Hospital
Boston, MA
Carilion Roanoke Memorial Hospital
Roanoke, VA
Cedars-Sinai Medical Center
Los Angeles, CA
Corewell Health Butterworth Hospital
Grand Rapids, MI
Duke University Hospital
Durham, NC
El Camino Health
Mountain View, CA
Emory University Hospital Midtown
Atlanta, GA
Hartford Hospital
Hartford, CT
HCA Florida JFK Hospital
Atlantis, FL
HCA Florida North Florida Hospital
Gainesville, FL
Henry Ford St. John Hospital (Detroit)
Detroit, MI
Houston Methodist Hospital
Houston, TX
Inova Fairfax Medical Campus
Falls Church, VA
INTEGRIS Health Heart Hospital at Baptist Medical Center
Oklahoma City, OK
Jersey Shore University Medical Center
Neptune, NJ
Kaiser Permanente San Francisco Medical Center
San Francisco, CA
Keck Hospital of USC
Los Angeles, CA
Lankenau Medical Center
Wynnewood, PA
Los Robles Regional Medical Center
Thousand Oaks, CA
M Health Fairview University of Minnesota Medical Center (East Bank)
Minneapolis, MN
Massachusetts General Hospital
Boston, MA
MedStar Washington Hospital Center
Washington, DC
MercyOne Des Moines Medical Center
Des Moines, IA
Methodist Hospital
San Antonio, TX
Montefiore Einstein Hospital (Moses Campus)
Bronx, NY
Morristown Medical Center
Morristown, NJ
Morton Plant Hospital (Clearwater)
Clearwater, FL
Northwestern Memorial Hospital
Chicago, IL
NYU Langone Health
New York, NY
OhioHealth Riverside Methodist Hospital
Columbus, OH
OHSU Hospital
Portland, OR
Piedmont Atlanta Hospital
Atlanta, GA
PIH Health Good Samaritan Hospital
Los Angeles, CA
Providence Sacred Heart Medical Center & Children's Hospital
Spokane, WA
Providence St. Patrick Hospital
Missoula, MT
Providence St. Vincent Medical Center
Portland, OR
Rush University Medical Center
Chicago, IL
Sandra Atlas Bass Heart Hospital at North Shore University Hospital
Manhasset, NY
Scripps Memorial Hospital La Jolla
La Jolla, CA
Sentara Norfolk General Hospital
Norfolk, VA
St. Francis Hospital & Heart Center
Roslyn, NY
Stanford Health Care
Stanford, CA
Swedish Cherry Hill Campus
Seattle, WA
Texas Health Dallas
Dallas, TX
The Christ Hospital
Cincinnati, OH
The Johns Hopkins Hospital
Baltimore, MD
The Mount Sinai Hospital
New York, NY
The Ohio State University Wexner Medical Center
Columbus, OH
The University of Kansas Health System
Kansas City, KS
The University of Vermont Medical Center
Burlington, VT
UAB Hospital
Birmingham, AL
University Hospitals Cleveland Medical Center
Cleveland, OH
University Medical Center
Charlottesville, VA
University of Maryland Medical Center
Baltimore, MD
University of Michigan Health System
Ann Arbor, MI
University of Washington Medical Center
Seattle, WA
UPMC Harrisburg
Harrisburg, PA
UPMC Presbyterian Shadyside
Pittsburgh, PA
Vanderbilt University Medical Center
Nashville, TN
Winchester Medical Center
Winchester, VA
Yale New Haven Hospital
New Haven, CT
Registry entry updated 2026-09-15
Deciding whether to join a study is your choice, and you can ask a study team questions before you decide anything.
If you would rather we did it with you, call us on (656) 206-4686.