Active, not recruitingNCT04375332
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Beating Heart Mitral Valve Repair With the HARPOON™ System
AI Description
The objective of the study is to evaluate the safety and effectiveness of the HARPOON™ System in the treatment of patients with severe degenerative mitral regurgitation (DMR).
- Who can join
- adult, older adult
- Participants
- 25
- Expected completion
- 2027-12-20
- Funded by
- industry
Conditions studied
Mitral Regurgitation
What is being tested
- DEVICE: HARPOON™ Beating Heart Mitral Valve Repair System
What it measures
- Change in NYHA classification from Baseline to 5 years, The New York Heart Association (NYHA) functional classification system relates symptoms to everyday activities and the patient's quality of life. Class I. Patients with cardiac disease but without resulting limitation of physical activity. Class II. Patients with cardiac disease resulting in slight limitation of physical activity. They are comfortable at rest. Class III. Patients with cardiac disease resulting in marked limitation of physical activity. They are comfortable at rest. Class IV. Patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms of heart failure or the anginal syndrome may be present even at rest., Baseline compared to 1 and 5 years
Centers Participating
These centers are participating in this study. Reach out to them directly to learn more.
Intermountain Medical Center
Murray, UT
Mayo Clinic (Rochester, Minnesota)
Rochester, MN
OHSU Hospital
Portland, OR
Piedmont Atlanta Hospital
Atlanta, GA
The Johns Hopkins Hospital
Baltimore, MD
TriStar Centennial Medical Center
Nashville, TN
UCSF Health
San Francisco, CA
University of Maryland Medical Center
Baltimore, MD
University of Michigan Health System
Ann Arbor, MI
Registry entry updated 2026-08-19
Deciding whether to join a study is your choice, and you can ask a study team questions before you decide anything.
If you would rather we did it with you, call us on (656) 206-4686.