RecruitingNCT04688190

CHOICE-MI

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry

Universitätsklinikum Hamburg-EppendorfMultiple US sitesView on ClinicalTrials.gov

AI Description

This multinational, investigator-initiated registry aims to investigate clinical outcomes of patients undergoing transcatheter mitral valve replacement (TMVR). The registry primarily focuses on patients treated with TMVR in real-world clinical practice.

Patients evaluated for TMVR but not undergoing the procedure are no longer systematically included. Historical data may include such patients who subsequently underwent alternative treatments, including transcatheter edge-to-edge repair, mitral valve surgery, or medical/conservative therapy.

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Who can join
adult, older adult
Participants
1000
Expected completion
2030-12-31
Funded by
other

Conditions studied

Mitral Annular Calcification, Mitral Regurgitation, Mitral Valve Disease

What it measures

  • Freedom from device-related complications, 30 days
  • Mitral insufficiency grade 2+ or more, Mitral insufficiency measured by transthoracic echocardiography. Assessment of MI severity according to current guidelines (ESC/EACTS and ACC/AHA) for valvular heart disease., 12 months

Working with

Montreal Heart Institute, University Hospital, Bordeaux

Centers Participating

These centers are participating in this study. Reach out to them directly to learn more.

Data Sources and Methodology

Registry entry updated 2026-05-07

Deciding whether to join a study is your choice, and you can ask a study team questions before you decide anything.

If you would rather we did it with you, call us on (656) 206-4686.