Cephea Early Feasibility Study
AI Description
The objective of this study is to evaluate the preliminary safety and effectiveness of the Cephea Mitral Valve System for the treatment of symptomatic patients with mitral valve disease (including mitral regurgitation, mitral stenosis and mixed mitral valve disease) in whom transcatheter therapy is deemed more appropriate than open heart surgery.
- Who can join
- adult, older adult
- Participants
- 90
- Expected completion
- 2031-03-01
- Funded by
- industry
Conditions studied
Mitral Regurgitation
What is being tested
- DEVICE: Cephea Mitral Valve System
What it measures
- Primary Effectiveness Endpoint, Proportion of subjects with reduction of MR to ≤ Grade I, will be assessed at 30 days post implant., 30 days post implant
- Primary Safety Endpoint, Freedom from all-cause mortality, which will be assessed at 30 days post implant., 30 days post implant
Centers Participating
These centers are participating in this study. Reach out to them directly to learn more.
Abbott Northwestern Hospital
Minneapolis, MN
Allegheny General Hospital
Pittsburgh, PA
Ascension Saint Thomas Hospital
Nashville, TN
Ascension Via Christi (Wichita)
Wichita, KS
Atrium Health Carolinas Medical Center
Charlotte, NC
Banner – University Medical Center Phoenix
Phoenix, AZ
Cedars-Sinai Medical Center
Los Angeles, CA
Cleveland Clinic
Cleveland, OH
Emory University Hospital Midtown
Atlanta, GA
Houston Methodist Hospital
Houston, TX
Los Robles Regional Medical Center
Thousand Oaks, CA
Montefiore Einstein Hospital (Moses Campus)
Bronx, NY
Northwestern Memorial Hospital
Chicago, IL
Piedmont Atlanta Hospital
Atlanta, GA
Sentara Norfolk General Hospital
Norfolk, VA
Swedish Cherry Hill Campus
Seattle, WA
UC Davis Medical Center
Sacramento, CA
University of Michigan Health System
Ann Arbor, MI
Vanderbilt University Medical Center
Nashville, TN
Registry entry updated 2026-09-11
Deciding whether to join a study is your choice, and you can ask a study team questions before you decide anything.
If you would rather we did it with you, call us on (656) 206-4686.