MRI-TAVR
MRI in Transcatheter Aortic Valve Replacement Patients
AI Description
The hypothesis is that SEV result in superior valvular hemodynamics (more pronounced during exercise) and exercise capacity relative to BEV. Furthermore, the hypothesis is that stress CMR will be able to demonstrate differences in these hemodynamic parameters. CMR will also provide refined assessment of paravalvular leak and its impact on ventricular function and on clinical outcomes.
- Who can join
- adult, older adult
- Participants
- 90
- Expected completion
- 2026-12-30
- Funded by
- other
Conditions studied
Aortic Valve Stenosis
What is being tested
- DEVICE: Balloon-expanding valve (Edwards Sapien 3 Ultra RESILIA)
- DEVICE: Self-expanding valve (Medtronic Evolut FX)
What it measures
- Effective orifice area (EOA), Change in effective orifice area (EOA) assessed by CMR between baseline and 1-year follow up (cm2), Baseline, 30-days and 1-year
- Mean gradient, Mean AV gradient assessed by CMR (mmHg), 1-year
- Peak gradient, Mean AV gradient assessed by CMR (mmHg), 1-year
Centers Participating
These centers are participating in this study. Reach out to them directly to learn more.
Registry entry updated 2025-12-17
Deciding whether to join a study is your choice, and you can ask a study team questions before you decide anything.
If you would rather we did it with you, call us on (656) 206-4686.