SMARTER-CMR
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance
AI Description
This is a multi-center, prospective, observational study designed to evaluate the impact of LV myocardial fibrosis extent assessed by CMR on LV reverse remodeling and clinical outcomes post TEER. The target sample will be up to 125 patients enrolled to achieve 100 evaluable at 6 months of follow-up. Enrollment will occur at up to eight centers.
- Who can join
- adult, older adult
- Participants
- 125
- Expected completion
- 2027-07
- Funded by
- other
Conditions studied
Functional Mitral Regurgitation, Heart Failure and Reduced Ejection Fraction
What is being tested
- DIAGNOSTIC_TEST: Cardiac MRI
What it measures
- Estimate the association between LV myocardial fibrosis by CMR late gadolinium enhancement imaging before TEER with LV reverse remodeling., change in LV end-diastolic volume index \[LVEDVi\] 6 months after TEER, From enrollment to the end of 6 months
Centers Participating
These centers are participating in this study. Reach out to them directly to learn more.
Registry entry updated 2025-12-23
Deciding whether to join a study is your choice, and you can ask a study team questions before you decide anything.
If you would rather we did it with you, call us on (656) 206-4686.