DMR
Transcatheter vs. Surgical Treatment of Degenerative Mitral Regurgitation
AI Description
The goal of this observational study is to compare the outcomes of transcatheter edge-to-edge repair (TEER) versus surgical mitral valve repair for degenerative mitral regurgitation (DMR) over the long term. The study aims to:
1. Evaluate the effectiveness and safety of TEER versus surgery in patients with DMR over long term. 2. Investigate the predictors of left ventricular dysfunction and clinical outcomes using advanced imaging techniques, such as cardiac MRI 3. Assess patient-reported recovery and quality of life outcomes using validated tools.
The study focuses on improving care strategies for patients with DMR, particularly those at higher surgical risk, by identifying optimal treatment approaches and predictors of recovery.
- Who can join
- adult, older adult
- Participants
- 60
- Expected completion
- 2027-08
- Funded by
- other
Conditions studied
Degenerative Mitral Valve Disease
What it measures
- Composite of all-cause mortality, heart failure hospitalization, and valve re-intervention, Composite of all-cause mortality, heart failure hospitalization, and valve re-intervention, From procedure to 3 years after procedure
Working with
National Heart, Lung, and Blood Institute (NHLBI)
Centers Participating
These centers are participating in this study. Reach out to them directly to learn more.
Registry entry updated 2026-05-26
Deciding whether to join a study is your choice, and you can ask a study team questions before you decide anything.
If you would rather we did it with you, call us on (656) 206-4686.