Who It’s For
Originally for people considered too high-risk for open chest surgery. Today it also reaches patients who could have surgery but want a faster recovery, and outcomes are often as good or better.
Heart valve treatment options, all in one place.
Find centers and clinical trials that treat heart valve disease — where they are, what they offer, and how to reach them. The HIP is here to help you on your care journey.
- 747 heart valve locations
- 89 recruiting clinical trials
- Fully independent
The HIP database by NexVal brings together information about transcatheter heart valve care using AI-assisted research. Learn more
Disclaimer: The HIP is not providing medical advice, diagnosis, or treatment recommendations. The HIP is made available to individuals for general informational purposes only. The information available through the HIP was gathered in whole or in part using artificial intelligence tools that have not been independently verified, and therefore the information provided on the HIP may be incomplete, contain errors, omissions, or outdated details. An individual using the HIP is strongly encouraged to consult the individual’s health care provider regarding treatment options, including participating in a clinical trial. The HIP is not making a clinical recommendation or endorsement of any academic medical center, hospital or physician or that an individual should pursue a particular clinical treatment. The HIP is not liable for whether any center accepts your insurance or whether your insurance covers any services. Confirm insurance acceptance and coverage directly with the center and your insurance provider. Using the HIP website does not create a patient-provider relationship. Do not disregard professional medical advice or delay seeking care because of information presented on the HIP. If you think you may have a medical emergency, call 911 or seek emergency care immediately.
Minimally Invasive Valve Therapy
Treating a valve without opening the chest
Instead of open chest surgery, physicians reach the valve through a thin tube called a catheter — usually threaded in through a blood vessel near the groin. The new valve is guided into place while your heart keeps beating, with no chest incision and no heart-lung machine.
Most patients are up and walking the next day, and home within two to three days.
Why You May Not Have Heard of It
These procedures are newer, and not every hospital has physicians who perform them. Training varies, and referrals often stop at a hospital’s own capabilities. It usually isn’t anyone’s fault — but it means the answer you get depends on who you ask.
Where Clinical Trials Fit
A clinical trial is a supervised study of a treatment that isn’t yet widely approved. When no cleared device exists for your valve, a trial can be the way to reach receive care earlier.
Who Built This
A physician, a philanthropist, and a digital team working to close the information gap
The Heart Information Portal (HIP) is an independent initiative of NexVal Medical, a nonprofit dedicated to improving access to minimally invasive valve therapies.
Many patients are never told these alternatives exist — or don’t know how to find a location that performs them.
We are not a medical provider. We are in information resource. We don’t bill insurance, we don’t take money from device makers, and we have no financial stake in what you decide. That is what lets us help you identify a center that could be an option for your care needs.
Philanthropic and Fully Independent NexVal Medical is not affiliated with any medical device manufacturer.
Hiram Bezerra, MD
Founding physician, NexVal Medical
Practicing interventional cardiologist focused on structural heart disease and transcatheter valve therapies
How the HIP Helps
Before you accept “nothing more can be done”
With valve disease, the answer you get may depend on who you ask.
“Nothing more can be done.”
Second or Third Opinion
An additional opinion from another interventional cardiologist
Clinical Trial
Clinical trials may offer options to eligible patients
NexVal Centers
Learn more
Connect with the HIP
The HIP team can help you explore information about treatments, centers, and trials — and prepare for a conversation with your care team.
NexVal Centers
The NexVal Center Commitment
Through AI, the HIP maps every center offering transcatheter valve therapies in the United States.
A NexVal Center has agreed to a set of commitments to patients who arrive through the HIP. NexVal Centers have committed to providing a designated point of contact and to accepting requests for case review from individuals who are not already patients in their systems. If they cannot provide the requested service, they have committed to helping patients explore other centers or clinical trials.
That last commitment is unusual. Most referral pathways end where a hospital’s own capabilities end.
NexVal Centers are not a clinical ranking or accreditation — they are centers that have agreed to these patient commitments.
Clinical Trials
Explore clinical trials for minimally invasive transcatheter heart valve procedures.
Valve disease research is rapidly advancing. Verified trials give eligible patients access to next-generation transcatheter valve therapies, mitral repair devices, and structural heart registries — matched to your diagnosis and preferred location.
Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
- Public sites
- 54
- Start date
- Jun 20, 2022
Recruiting
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System
- Public sites
- 10
- Start date
- Jul 14, 2020
Recruiting
TRIVITA
VDyne Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)
- Public sites
- 1
- Start date
- Jul 28, 2026
Explore information that may be relevant to you
Results are provided for informational purposes only and are not medical advice or a determination that a treatment, center, or clinical trial is appropriate for you. Discuss your options with a qualified healthcare professional.