Cedars-Sinai Medical Center

Research CenterTreats all valves

AI Description

Cedars-Sinai’s Smidt Heart Institute provides surgical and catheter-based valve repair and replacement, including TAVR, robotic mitral valve repair, percutaneous mitral repair with MitraClip, and transcatheter mitral and tricuspid procedures. Care is provided by a multidisciplinary team of interventional cardiologists, cardiac surgeons, imaging specialists and other heart specialists, with treatment for disease affecting all four heart valves.

This description was generated by AI based on public sources. Data Sources and Methodology · Report inaccurate information

Location and Contact

8700 Beverly Blvd
Los Angeles, CA 90048

Clinical Trials

Active, not recruiting

CLASP IID/IIF

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial

Public sites
60
Start date
Nov 30, 2018
Active, not recruiting

SURTAVI

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

Public sites
56
Start date
Apr 1, 2012
Recruiting

ARTIST

ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

Public sites
32
Start date
Jun 18, 2025
Recruiting

ATLAS

ATLAS (AltaValve) Pivotal Trial

Public sites
30
Start date
Sep 3, 2024
Recruiting

BELIEVE-IT

Bicuspid Aortic Valve Replacement: Evaluation of Transcatheter Versus Surgery-Pilot Trial

Public sites
1
Start date
Jan 31, 2025
Recruiting

VISTA-US

Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)

Public sites
9
Start date
Apr 1, 2024
Active, not recruiting

SUMMIT

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Public sites
71
Start date
Jun 15, 2018
Active, not recruiting

EARLY TAVR

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis

Public sites
66
Start date
Jul 12, 2017
Recruiting

CLASP II TR

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Public sites
70
Start date
Dec 11, 2019
Recruiting

JOURNEY

J-Valve Transfemoral Pivotal Study

Public sites
31
Start date
Oct 17, 2024
Active, not recruiting

P3

PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis

Public sites
62
Start date
Mar 1, 2016
Recruiting

PROGRESS

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

Public sites
57
Start date
Oct 12, 2021
Active, not recruiting

PRIMARY

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

Public sites
22
Start date
Feb 21, 2022
Active, not recruiting

PORTICO-IDE

Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial

Public sites
59
Start date
May 1, 2014
Recruiting

CASSINI-US

Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)

Public sites
4
Start date
Aug 5, 2026
Active, not recruiting

SAPIEN M3 EFS

SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation

Public sites
8
Start date
Sep 14, 2017
Active, not recruiting

SMART

SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial

Public sites
59
Start date
Apr 2, 2021
Recruiting

BELIEVERS

TAVR vs SAVR in Severe Bicuspid Aortic Stenosis

Public sites
1
Start date
Jul 23, 2026
Recruiting

TWIST-EFS

TVMR With the INNOVALVE System Trial - Early Feasibility Study

Public sites
19
Start date
Sep 1, 2022
Recruiting

ENCIRCLE

The ENCIRCLE Trial

Public sites
52
Start date
Nov 12, 2020
Active, not recruiting

JENA-VAD

The JenaValve ALIGN-AR LVAD Registry

Public sites
13
Start date
Dec 9, 2024
Active, not recruiting

ALIGN-AR

The JenaValve ALIGN-AR Pivotal Trial

Public sites
29
Start date
May 22, 2020
Recruiting

MITRAL-II

The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

Public sites
13
Start date
Mar 8, 2021
Recruiting

APOLLO

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Public sites
71
Start date
Oct 23, 2017
Recruiting

CHOICE-MI

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry

Public sites
9
Start date
Nov 1, 2020
Recruiting

DMR

Transcatheter vs. Surgical Treatment of Degenerative Mitral Regurgitation

Public sites
1
Start date
Feb 19, 2025
Recruiting

PRIMARY SDM

Patient-Centered Approach for Treatment Decisions in Mitral Valve Prolapse

Public sites
5
Start date
Sep 1, 2023
Recruiting

RESOLVE

Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With Anticoagulation

Public sites
1
Start date
Dec 1, 2014

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